Paradoxical sleep deprivation increases plasma endothelin levels

The endothelins (ET-1, 2 and 3) constitute a family of 21 amino acid peptides with potent biological activities.ET-1 is one of the most potent endogenous vasoconstrictors so far identified and its increased concentration in plasma appears Food Service to be closely related to the pathogenesis of arterial hypertension as well as to obstructive sleep

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Acute Effects of Moderate and Strenuous Running on Trace Element Distribution in the Brain, Liver, and Spleen of Trained Rats

Objective: Trace elements such as manganese (Mn), cobalt (Co) and chromium (Cr) play key roles in metabolic reactions and are important in many physiological enzymatic processes.In this study, we aimed to investigate the acute effects of moderate and strenuous running (treadmill) exercise on the levels of Mn, Co and Cr in the Hair Bands brain, live

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From Biology to Therapy: The CLL Success Story

Abstract.Chemoimmunotherapy has been the standard of care for patients with chronic lymphocytic leukemia (CLL) over the last decade.Advances in monoclonal antibody technology have resulted in the development of newer generations of anti-CD20 antibodies with improved therapeutic effectiveness.In parallel, our knowledge about the distinctive biologic

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